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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
18.18
Human Site:
S515
Identified Species:
25
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S515
T
P
N
S
F
G
A
S
K
P
C
T
E
P
V
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S515
T
P
N
S
F
G
A
S
K
P
C
T
E
P
V
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S636
T
P
N
S
F
G
A
S
K
P
C
T
E
P
V
Dog
Lupus familis
XP_543550
1017
111618
S515
T
P
N
S
F
G
A
S
K
P
S
T
E
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
K515
T
P
S
F
G
A
S
K
P
C
T
E
P
V
A
Rat
Rattus norvegicus
NP_001129232
1015
111665
K515
T
P
S
F
G
A
S
K
P
C
T
E
P
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S515
L
D
S
N
A
A
N
S
L
N
T
S
K
P
S
Frog
Xenopus laevis
Q8QFR2
1013
112021
L515
T
T
S
S
S
G
A
L
K
S
N
V
E
L
V
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
D515
L
G
L
R
P
S
H
D
P
S
T
T
S
P
N
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
L515
G
Q
A
P
P
L
G
L
R
P
S
Q
D
P
M
Fruit Fly
Dros. melanogaster
O17468
1047
113397
P512
D
S
R
L
K
T
Q
P
A
S
Q
R
R
Q
S
Honey Bee
Apis mellifera
XP_001122939
838
91355
P361
E
L
G
Q
P
L
D
P
A
E
Q
S
S
L
H
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
E458
N
S
E
K
T
M
M
E
E
R
N
K
Q
I
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
D487
Q
R
E
Y
R
R
P
D
G
R
K
R
I
I
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
D515
A
A
A
P
A
K
G
D
S
G
D
F
P
V
E
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
S363
N
K
S
I
T
D
M
S
W
N
P
D
G
S
L
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
S513
S
S
G
T
G
L
S
S
L
P
Q
A
Q
L
V
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
N.A.
13.3
46.6
13.3
13.3
0
0
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
26.6
N.A.
N.A.
40
53.3
13.3
33.3
0
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
0
6.6
20
P-Site Similarity:
N.A.
0
N.A.
0
20
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
12
0
12
18
30
0
12
0
0
6
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
18
0
0
0
0
% C
% Asp:
6
6
0
0
0
6
6
18
0
0
6
6
6
0
6
% D
% Glu:
6
0
12
0
0
0
0
6
6
6
0
12
30
0
6
% E
% Phe:
0
0
0
12
24
0
0
0
0
0
0
6
0
0
0
% F
% Gly:
6
6
12
0
18
30
12
0
6
6
0
0
6
0
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
6
% H
% Ile:
0
0
0
6
0
0
0
0
0
0
0
0
6
12
0
% I
% Lys:
0
6
0
6
6
6
0
12
30
0
6
6
6
0
0
% K
% Leu:
12
6
6
6
0
18
0
12
12
0
0
0
0
18
6
% L
% Met:
0
0
0
0
0
6
12
0
0
0
0
0
0
0
6
% M
% Asn:
12
0
24
6
0
0
6
0
0
12
12
0
0
0
6
% N
% Pro:
0
36
0
12
18
0
6
12
18
36
6
0
18
42
6
% P
% Gln:
6
6
0
6
0
0
6
0
0
0
18
6
12
6
0
% Q
% Arg:
0
6
6
6
6
6
0
0
6
12
0
12
6
0
0
% R
% Ser:
6
18
30
30
6
6
18
42
6
18
12
12
12
6
12
% S
% Thr:
42
6
0
6
12
6
0
0
0
0
24
30
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
6
0
18
36
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _